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Enhanced expression of ROCK in left atrial myocytes of mitral regurgitation: a potential mechanism of myolysis

BACKGROUND: Severe mitral regurgitation (MR) may cause myolysis in the left atrial myocytes. Myolysis may contribute to atrial enlargement. However, the relationship between Rho-associated kinase (ROCK) and myolysis in the left atrial myocytes of MR patients remain unclear. METHODS: This study compr...

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Detalles Bibliográficos
Autores principales: Chen, Huang-Chung, Chang, Jen-Ping, Chang, Tzu-Hao, Lin, Yu-Sheng, Huang, Yao-Kuang, Pan, Kuo-Li, Fang, Chih-Yuan, Chen, Chien-Jen, Ho, Wan-Chun, Chen, Mien-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429363/
https://www.ncbi.nlm.nih.gov/pubmed/25956928
http://dx.doi.org/10.1186/s12872-015-0038-9