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Restin suppressed epithelial-mesenchymal transition and tumor metastasis in breast cancer cells through upregulating mir-200a/b expression via association with p73

BACKGROUND: Restin belongs to MAGE superfamily and is known as MAGE H1. Restin was firstly cloned from HL-60 cells treated with all-trans retinoic acid (ATRA). Previous studies showed a pro-apoptotic role of Restin in several cell lines. However, little information is available on its expression pat...

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Detalles Bibliográficos
Autores principales: Lu, Zhenduo, Jiao, Dechuang, Qiao, Jianghua, Yang, Sen, Yan, Min, Cui, Shude, Liu, Zhenzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429374/
https://www.ncbi.nlm.nih.gov/pubmed/25972084
http://dx.doi.org/10.1186/s12943-015-0370-9