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Pharmacologically relevant doses of valproate upregulate CD20 expression in three diffuse large B-cell lymphoma patients in vivo

BACKGROUND: Epigenetic code modifications by histone deacetylase inhibitors (HDACi) have been proposed as potential new therapies for lymphoid malignancies. Diffuse large B-cell lymphoma (DLBCL) is the most common type of aggressive lymphoma for which standard first line treatment is the chemotherap...

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Detalles Bibliográficos
Autores principales: Damm, Jesper Kofoed, Gordon, Sandra, Ehinger, Mats, Jerkeman, Mats, Gullberg, Urban, Hultquist, Anne, Drott, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429466/
https://www.ncbi.nlm.nih.gov/pubmed/25973343
http://dx.doi.org/10.1186/2162-3619-4-4