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The female protective effect in autism spectrum disorder is not mediated by a single genetic locus

BACKGROUND: A 4:1 male to female sex bias has consistently been observed in autism spectrum disorder (ASD). Epidemiological and genetic studies suggest a female protective effect (FPE) may account for part of this bias; however, the mechanism of such protection is unknown. Quantitative assessment of...

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Detalles Bibliográficos
Autores principales: Gockley, Jake, Willsey, A Jeremy, Dong, Shan, Dougherty, Joseph D, Constantino, John N, Sanders, Stephan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429476/
https://www.ncbi.nlm.nih.gov/pubmed/25973162
http://dx.doi.org/10.1186/s13229-015-0014-3