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The female protective effect in autism spectrum disorder is not mediated by a single genetic locus
BACKGROUND: A 4:1 male to female sex bias has consistently been observed in autism spectrum disorder (ASD). Epidemiological and genetic studies suggest a female protective effect (FPE) may account for part of this bias; however, the mechanism of such protection is unknown. Quantitative assessment of...
Autores principales: | Gockley, Jake, Willsey, A Jeremy, Dong, Shan, Dougherty, Joseph D, Constantino, John N, Sanders, Stephan J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429476/ https://www.ncbi.nlm.nih.gov/pubmed/25973162 http://dx.doi.org/10.1186/s13229-015-0014-3 |
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