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An unexpected alliance between stress responses to drive oncogenesis

XBP1 is a well-characterized regulator of the unfolding protein response that is activated in response to unfolded or misfolded proteins or nutrient deprivation. The conventional wisdom is that XBP1 is activated to coordinate the unfolded protein response and promote cellular survival under stresses...

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Detalles Bibliográficos
Autores principales: Keenan, Melissa M, Ding, Chien-Kuang Cornelia, Chi, Jen-Tsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429501/
https://www.ncbi.nlm.nih.gov/pubmed/25927911
http://dx.doi.org/10.1186/s13058-014-0471-1