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The combination of sorafenib and everolimus shows antitumor activity in preclinical models of malignant pleural mesothelioma
BACKGROUND: Malignant Pleural Mesothelioma (MPM) is an aggressive tumor arising from mesothelial cells lining the pleural cavities characterized by resistance to standard therapies. Most of the molecular steps responsible for pleural transformation remain unclear; however, several growth factor sign...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429519/ https://www.ncbi.nlm.nih.gov/pubmed/25952930 http://dx.doi.org/10.1186/s12885-015-1363-1 |