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Hepatitis B virus replication and sex-determining region Y box 4 production are tightly controlled by a novel positive feedback mechanism

Hepatitis B virus (HBV) infection is a major cause of liver diseases. However, the mechanisms underlying HBV infection and pathogenesis remain largely unknown. The sex-determining region Y box 4 (Sox4) is a transcriptional factor, which preferentially regulates the development of various organs, tis...

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Detalles Bibliográficos
Autores principales: Shang, Jian, Zheng, Yuan, Guo, Xiaohong, Mo, Jiayin, Xie, Xueping, Xiong, Ying, Liu, Yingle, Wu, Kailang, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429541/
https://www.ncbi.nlm.nih.gov/pubmed/25970172
http://dx.doi.org/10.1038/srep10066