ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice

Iron overload, caused by hereditary hemochromatosis or repeated blood transfusions in some diseases, such as beta thalassemia, bone marrow failure and myelodysplastic syndrome, can significantly induce injured bone marrow (BM) function as well as parenchyma organ dysfunctions. However, the effect of...

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Detalles Bibliográficos
Autores principales: Chai, Xiao, Li, Deguan, Cao, Xiaoli, Zhang, Yuchen, Mu, Juan, Lu, Wenyi, Xiao, Xia, Li, Chengcheng, Meng, Juanxia, Chen, Jie, Li, Qing, Wang, Jishi, Meng, Aimin, Zhao, Mingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429544/
https://www.ncbi.nlm.nih.gov/pubmed/25970748
http://dx.doi.org/10.1038/srep10181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429544/
https://www.ncbi.nlm.nih.gov/pubmed/25970748
http://dx.doi.org/10.1038/srep10181

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