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ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice
Iron overload, caused by hereditary hemochromatosis or repeated blood transfusions in some diseases, such as beta thalassemia, bone marrow failure and myelodysplastic syndrome, can significantly induce injured bone marrow (BM) function as well as parenchyma organ dysfunctions. However, the effect of...
Autores principales: | Chai, Xiao, Li, Deguan, Cao, Xiaoli, Zhang, Yuchen, Mu, Juan, Lu, Wenyi, Xiao, Xia, Li, Chengcheng, Meng, Juanxia, Chen, Jie, Li, Qing, Wang, Jishi, Meng, Aimin, Zhao, Mingfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429544/ https://www.ncbi.nlm.nih.gov/pubmed/25970748 http://dx.doi.org/10.1038/srep10181 |
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