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Preclinical Effectiveness of Selective Inhibitor of IRS-1/2 NT157 in Osteosarcoma Cell Lines

Osteosarcoma (OS) is the most common primary bone tumor in children and young adults. Several studies have confirmed the involvement of the insulin-like growth factor (IGF) system in the regulation of OS cell proliferation and differentiation as well as in the protection of cells from chemotherapy....

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Detalles Bibliográficos
Autores principales: Garofalo, Cecilia, Capristo, Mariantonietta, Mancarella, Caterina, Reunevi, Hadas, Picci, Piero, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429561/
https://www.ncbi.nlm.nih.gov/pubmed/26029165
http://dx.doi.org/10.3389/fendo.2015.00074