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Use of Longitudinal Dose–Response Modeling to Support the Efficacy and Tolerability of Alitretinoin in Severe Refractory Chronic Hand Eczema (CHE)

Longitudinal dose–response analyses of alitretinoin (an investigational agent in the US) were conducted to supplement results from phase III studies in severe, refractory chronic hand eczema, with objectives to address several outstanding development issues (e.g., optimal dose, possible factors affe...

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Detalles Bibliográficos
Autores principales: Schmith, GD, Singh, R, Gomeni, R, Graff, O, Hamedani, AG, Troughton, JS, Learned, SM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429579/
https://www.ncbi.nlm.nih.gov/pubmed/26225249
http://dx.doi.org/10.1002/psp4.24