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Use of Longitudinal Dose–Response Modeling to Support the Efficacy and Tolerability of Alitretinoin in Severe Refractory Chronic Hand Eczema (CHE)
Longitudinal dose–response analyses of alitretinoin (an investigational agent in the US) were conducted to supplement results from phase III studies in severe, refractory chronic hand eczema, with objectives to address several outstanding development issues (e.g., optimal dose, possible factors affe...
Autores principales: | Schmith, GD, Singh, R, Gomeni, R, Graff, O, Hamedani, AG, Troughton, JS, Learned, SM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429579/ https://www.ncbi.nlm.nih.gov/pubmed/26225249 http://dx.doi.org/10.1002/psp4.24 |
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