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Dynamic Modeling of the Interaction Between Autophagy and Apoptosis in Mammalian Cells

Autophagy is a conserved biological stress response in mammalian cells that is responsible for clearing damaged proteins and organelles from the cytoplasm and recycling their contents via the lysosomal pathway. In cases of mild stress, autophagy acts as a survival mechanism, while in cases of severe...

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Detalles Bibliográficos
Autores principales: Tavassoly, I, Parmar, J, Shajahan-Haq, AN, Clarke, R, Baumann, WT, Tyson, JJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429580/
https://www.ncbi.nlm.nih.gov/pubmed/26225250
http://dx.doi.org/10.1002/psp4.29