Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts

Reprogramming somatic cells from one cell fate to another can generate specific neurons suitable for disease modeling. To maximize the utility of patient-derived neurons, they must model not only disease-relevant cell classes but also the diversity of neuronal subtypes found in vivo and the pathophy...

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Detalles Bibliográficos
Autores principales: Wainger, Brian J., Buttermore, Elizabeth D., Oliveira, Julia T., Mellin, Cassidy, Lee, Seungkyu, Saber, Wardiya Afshar, Wang, Amy, Ichida, Justin K., Chiu, Isaac M., Barrett, Lee, Huebner, Eric A., Bilgin, Canan, Tsujimoto, Naomi, Brenneis, Christian, Kapur, Kush, Rubin, Lee L., Eggan, Kevin, Woolf, Clifford J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429606/
https://www.ncbi.nlm.nih.gov/pubmed/25420066
http://dx.doi.org/10.1038/nn.3886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429606/
https://www.ncbi.nlm.nih.gov/pubmed/25420066
http://dx.doi.org/10.1038/nn.3886

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