Heat shock protein 90 inhibitors repurposed against Entamoeba histolytica

Hsp90 is an essential chaperone responsible for trafficking a vast array of client proteins, which are substrates that Hsp90 regulates in eukaryotic cells under stress conditions. The ATP-binding N-terminal domain of Hsp90 (also known as a GHKL type ATPase domain) can serve as a specific drug target...

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Detalles Bibliográficos
Autores principales: Shahinas, Dea, Debnath, Anjan, Benedict, Christan, McKerrow, James H., Pillai, Dylan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429810/
https://www.ncbi.nlm.nih.gov/pubmed/26029171
http://dx.doi.org/10.3389/fmicb.2015.00368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429810/
https://www.ncbi.nlm.nih.gov/pubmed/26029171
http://dx.doi.org/10.3389/fmicb.2015.00368

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