Recurrence rates provide evidence for sex-differential, familial genetic liability for autism spectrum disorders in multiplex families and twins

BACKGROUND: Autism spectrum disorders (ASDs) are more prevalent in males, suggesting a multiple threshold liability model in which females are, on average, protected by sex-differential mechanisms. Under this model, autistic females are predicted to carry a more penetrant risk variant load than male...

Descripción completa

Detalles Bibliográficos
Autores principales: Werling, Donna M, Geschwind, Daniel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429923/
https://www.ncbi.nlm.nih.gov/pubmed/25973164
http://dx.doi.org/10.1186/s13229-015-0004-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429923/
https://www.ncbi.nlm.nih.gov/pubmed/25973164
http://dx.doi.org/10.1186/s13229-015-0004-5

Ejemplares similares