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ISOpureR: an R implementation of a computational purification algorithm of mixed tumour profiles

BACKGROUND: Tumour samples containing distinct sub-populations of cancer and normal cells present challenges in the development of reproducible biomarkers, as these biomarkers are based on bulk signals from mixed tumour profiles. ISOpure is the only mRNA computational purification method to date tha...

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Detalles Bibliográficos
Autores principales: Anghel, Catalina V, Quon, Gerald, Haider, Syed, Nguyen, Francis, Deshwar, Amit G, Morris, Quaid D, Boutros, Paul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429941/
https://www.ncbi.nlm.nih.gov/pubmed/25972088
http://dx.doi.org/10.1186/s12859-015-0597-x