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ISOpureR: an R implementation of a computational purification algorithm of mixed tumour profiles
BACKGROUND: Tumour samples containing distinct sub-populations of cancer and normal cells present challenges in the development of reproducible biomarkers, as these biomarkers are based on bulk signals from mixed tumour profiles. ISOpure is the only mRNA computational purification method to date tha...
Autores principales: | Anghel, Catalina V, Quon, Gerald, Haider, Syed, Nguyen, Francis, Deshwar, Amit G, Morris, Quaid D, Boutros, Paul C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429941/ https://www.ncbi.nlm.nih.gov/pubmed/25972088 http://dx.doi.org/10.1186/s12859-015-0597-x |
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