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The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output

Phosphoinositides (PI) are important signaling molecules in the nucleus that influence gene expression. However, if and how nuclear PI directly affects the transcriptional machinery is not known. We report that the lipid kinase PIP4K2B regulates nuclear PI5P and the expression of myogenic genes duri...

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Detalles Bibliográficos
Autores principales: Stijf-Bultsma, Yvette, Sommer, Lilly, Tauber, Maria, Baalbaki, Mai, Giardoglou, Panagiota, Jones, David R., Gelato, Kathy A., van Pelt, Jason, Shah, Zahid, Rahnamoun, Homa, Toma, Clara, Anderson, Karen E., Hawkins, Philip, Lauberth, Shannon M., Haramis, Anna-Pavlina G., Hart, Daniel, Fischle, Wolfgang, Divecha, Nullin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429956/
https://www.ncbi.nlm.nih.gov/pubmed/25866244
http://dx.doi.org/10.1016/j.molcel.2015.03.009