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Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF)

Multiple sclerosis (MS) is a progressive demyelinating disease of the central nervous system (CNS). Many nerve axons are insulated by a myelin sheath and their demyelination not only prevents saltatory electrical signal conduction along the axons but also removes their metabolic support leading to i...

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Detalles Bibliográficos
Autores principales: Rittchen, Sonja, Boyd, Amanda, Burns, Alasdair, Park, Jason, Fahmy, Tarek M., Metcalfe, Su, Williams, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429967/
https://www.ncbi.nlm.nih.gov/pubmed/25934281
http://dx.doi.org/10.1016/j.biomaterials.2015.03.044