Cargando…
Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF)
Multiple sclerosis (MS) is a progressive demyelinating disease of the central nervous system (CNS). Many nerve axons are insulated by a myelin sheath and their demyelination not only prevents saltatory electrical signal conduction along the axons but also removes their metabolic support leading to i...
Autores principales: | Rittchen, Sonja, Boyd, Amanda, Burns, Alasdair, Park, Jason, Fahmy, Tarek M., Metcalfe, Su, Williams, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429967/ https://www.ncbi.nlm.nih.gov/pubmed/25934281 http://dx.doi.org/10.1016/j.biomaterials.2015.03.044 |
Ejemplares similares
-
COVID-19 lockdown: de-risking exit by protecting the lung with leukaemia inhibitory factor (LIF)
por: Metcalfe, Su M.
Publicado: (2020) -
Multiple Sclerosis and the LIF/IL-6 Axis: Use of Nanotechnology to Harness the Tolerogenic and Reparative Properties of LIF
por: Metcalfe, Su M., et al.
Publicado: (2015) -
Diazoxide Promotes Oligodendrocyte Precursor Cell Proliferation and Myelination
por: Fogal, Birgit, et al.
Publicado: (2010) -
Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells
por: Giera, Stefanie, et al.
Publicado: (2018) -
Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival
por: Kougioumtzidou, Eleni, et al.
Publicado: (2017)