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Generation of a Functionally Distinct Rhizopus oryzae Lipase through Protein Folding Memory
Rhizopus oryzae lipase (ROL) has a propeptide at its N-terminus that functions as an intramolecular chaperone and facilitates the folding of mature ROL (mROL). In this study, we successfully generated a functionally distinct imprinted mROL (mROL(imp)) through protein folding memory using a mutated p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430139/ https://www.ncbi.nlm.nih.gov/pubmed/25970342 http://dx.doi.org/10.1371/journal.pone.0124545 |