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A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome

Cryptococcus neoformans is an opportunistic yeast that kills over 625,000 people yearly through lethal meningitis. Host phagocytes serve as the first line of defense against this pathogen, but fungal engulfment and subsequent intracellular proliferation also correlate with poor patient outcome. Defi...

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Detalles Bibliográficos
Autores principales: Santiago-Tirado, Felipe H., Peng, Tao, Yang, Meng, Hang, Howard C., Doering, Tamara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430228/
https://www.ncbi.nlm.nih.gov/pubmed/25970403
http://dx.doi.org/10.1371/journal.ppat.1004908