Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells

Annually, ovarian cancer (OC) affects 240,000 women worldwide and is the most lethal gynecological malignancy. High-grade serous OC (HGSOC) is the most common and aggressive OC subtype, characterized by widespread genome changes and chromosomal instability and is consequently poorly responsive to ch...

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Detalles Bibliográficos
Autores principales: Weiner-Gorzel, Karolina, Dempsey, Eugene, Milewska, Malgorzata, McGoldrick, Aloysius, Toh, Valerie, Walsh, Aoibheann, Lindsay, Sinead, Gubbins, Luke, Cannon, Aoife, Sharpe, Daniel, O'Sullivan, Jacintha, Murphy, Madeline, Madden, Stephen F, Kell, Malcolm, McCann, Amanda, Furlong, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430267/
https://www.ncbi.nlm.nih.gov/pubmed/25684390
http://dx.doi.org/10.1002/cam4.409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430267/
https://www.ncbi.nlm.nih.gov/pubmed/25684390
http://dx.doi.org/10.1002/cam4.409

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