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Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells
Annually, ovarian cancer (OC) affects 240,000 women worldwide and is the most lethal gynecological malignancy. High-grade serous OC (HGSOC) is the most common and aggressive OC subtype, characterized by widespread genome changes and chromosomal instability and is consequently poorly responsive to ch...
Autores principales: | Weiner-Gorzel, Karolina, Dempsey, Eugene, Milewska, Malgorzata, McGoldrick, Aloysius, Toh, Valerie, Walsh, Aoibheann, Lindsay, Sinead, Gubbins, Luke, Cannon, Aoife, Sharpe, Daniel, O'Sullivan, Jacintha, Murphy, Madeline, Madden, Stephen F, Kell, Malcolm, McCann, Amanda, Furlong, Fiona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430267/ https://www.ncbi.nlm.nih.gov/pubmed/25684390 http://dx.doi.org/10.1002/cam4.409 |
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