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Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability
Invadopodia are actin-rich cell membrane projections used by invasive cells to penetrate the basement membrane. Control of invadopodia stability is critical for efficient degradation of the extracellular matrix (ECM); however, the underlying molecular mechanisms remain poorly understood. Here, we un...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430312/ https://www.ncbi.nlm.nih.gov/pubmed/25486435 http://dx.doi.org/10.1038/onc.2014.388 |