Mechanisms of Nifedipine-Downregulated CD40L/sCD40L Signaling in Collagen Stimulated Human Platelets

The platelet-derived soluble CD40L (sCD40L) release plays a critical role in the development of atherosclerosis. Nifedipine, a dihydropyridine-based L-type calcium channel blocker (CCB), has been reported to have an anti-atherosclerotic effect beyond its blood pressure-lowering effect, but the molec...

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Detalles Bibliográficos
Autores principales: Chen, Tso-Hsiao, Shih, Ching-Yu, Hsu, Wen-Lin, Chou, Tz-Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430314/
https://www.ncbi.nlm.nih.gov/pubmed/25970603
http://dx.doi.org/10.1371/journal.pone.0127054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430314/
https://www.ncbi.nlm.nih.gov/pubmed/25970603
http://dx.doi.org/10.1371/journal.pone.0127054

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