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Parameters Influencing Baseline HIV-1 Genotypic Tropism Testing Related to Clinical Outcome in Patients on Maraviroc

OBJECTIVES: We analysed the impact of different parameters on genotypic tropism testing related to clinical outcome prediction in 108 patients on maraviroc (MVC) treatment. METHODS: 87 RNA and 60 DNA samples were used. The viral tropism was predicted using the geno2pheno([coreceptor]) and T-CUP tool...

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Detalles Bibliográficos
Autores principales: Sierra, Saleta, Dybowski, J. Nikolai, Pironti, Alejandro, Heider, Dominik, Güney, Lisa, Thielen, Alex, Reuter, Stefan, Esser, Stefan, Fätkenheuer, Gerd, Lengauer, Thomas, Hoffmann, Daniel, Pfister, Herbert, Jensen, Björn, Kaiser, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430318/
https://www.ncbi.nlm.nih.gov/pubmed/25970632
http://dx.doi.org/10.1371/journal.pone.0125502