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Activation of GPR55 Receptors Exacerbates oxLDL-Induced Lipid Accumulation and Inflammatory Responses, while Reducing Cholesterol Efflux from Human Macrophages

The G protein-coupled receptor GPR55 has been proposed as a new cannabinoid receptor associated with bone remodelling, nervous system excitability, vascular homeostasis as well as in several pathophysiological conditions including obesity and cancer. However, its physiological role and underlying me...

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Detalles Bibliográficos
Autores principales: Lanuti, Mirko, Talamonti, Emanuela, Maccarrone, Mauro, Chiurchiù, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430319/
https://www.ncbi.nlm.nih.gov/pubmed/25970609
http://dx.doi.org/10.1371/journal.pone.0126839