LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression

RNA-binding proteins (RBPs) bind to and post-transcriptionally regulate the stability of mRNAs. La-related protein 1 (LARP1) is a conserved RBP that interacts with poly-A-binding protein and is known to regulate 5′-terminal oligopyrimidine tract (TOP) mRNA translation. Here, we show that LARP1 is co...

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Detalles Bibliográficos
Autores principales: Mura, M, Hopkins, T G, Michael, T, Abd-Latip, N, Weir, J, Aboagye, E, Mauri, F, Jameson, C, Sturge, J, Gabra, H, Bushell, M, Willis, A E, Curry, E, Blagden, S P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430325/
https://www.ncbi.nlm.nih.gov/pubmed/25531318
http://dx.doi.org/10.1038/onc.2014.428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430325/
https://www.ncbi.nlm.nih.gov/pubmed/25531318
http://dx.doi.org/10.1038/onc.2014.428

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