Mucosal pemphigus vulgaris anti-Dsg3 IgG are pathogenic to the oral mucosa of humanized Dsg3 mice

There are two major clinical subsets of pemphigus vulgaris (PV), mucosal PV (mPV) and mucocutaneous PV (mcPV). The mPV subset exhibits anti-human desmoglein (Dsg) 3 autoantibodies that fail to recognize murine Dsg3; thus, passive transfer experiments of mPV IgG into WT mice have been unsuccessful at...

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Detalles Bibliográficos
Autores principales: Culton, Donna A., McCray, Suzanne K., Park, Moonhee, Roberts, James C., Li, Ning, Zedek, Daniel C., Anhalt, Grant J., Cowley, Dale, Liu, Zhi, Diaz, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430403/
https://www.ncbi.nlm.nih.gov/pubmed/25695683
http://dx.doi.org/10.1038/jid.2015.54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430403/
https://www.ncbi.nlm.nih.gov/pubmed/25695683
http://dx.doi.org/10.1038/jid.2015.54

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