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Caenorhabditis elegans as a Model System for Studying Drug Induced Mitochondrial Toxicity

Today HIV-1 infection is recognized as a chronic disease with obligatory lifelong treatment to keep viral titers below detectable levels. The continuous intake of antiretroviral drugs however, leads to severe and even life-threatening side effects, supposedly by the deleterious impact of nucleoside-...

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Detalles Bibliográficos
Autores principales: de Boer, Richard, Smith, Ruben L., De Vos, Winnok H., Manders, Erik M. M., Brul, Stanley, van der Spek, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430419/
https://www.ncbi.nlm.nih.gov/pubmed/25970180
http://dx.doi.org/10.1371/journal.pone.0126220