Loss of Murine FOXO3 in Cells of the Myeloid Lineage Enhances Myelopoiesis but Protects from K/BxN-Serum Transfer-Induced Arthritis

FOXO transcription factors have a highly conserved role in regulating transcription of genes involved in differentiation, cell cycle arrest, apoptosis and DNA repair. Loss of FOXO3 in mice has previously been shown to result in a myeloproliferative disease. In agreement with this, we found that an i...

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Detalles Bibliográficos
Autores principales: Kang, Hannah, Corr, Maripat, Mansson, Robert, Welinder, Eva, Hedrick, Stephen M., Stone, Erica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430473/
https://www.ncbi.nlm.nih.gov/pubmed/25969990
http://dx.doi.org/10.1371/journal.pone.0126728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430473/
https://www.ncbi.nlm.nih.gov/pubmed/25969990
http://dx.doi.org/10.1371/journal.pone.0126728

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