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Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection

The E2 glycoprotein of Hepatitis C virus (HCV) is a major target of the neutralizing antibody (NAb) response with the majority of epitopes located within its receptor binding domain (RBD; 384–661). Within E2 are three variable regions located at the N-terminus (HVR1; 384–411), and internally at 460–...

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Detalles Bibliográficos
Autores principales: Alhammad, Yousef M. O., Maharajh, Sanvir, Butcher, Rebecca, Eden, John-Sebastian, White, Peter A., Poumbourios, Pantelis, Drummer, Heidi E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430534/
https://www.ncbi.nlm.nih.gov/pubmed/25970466
http://dx.doi.org/10.1371/journal.pone.0126397