Novel Antimicrobial Peptides with High Anticancer Activity and Selectivity

We describe a strategy to boost anticancer activity and reduce normal cell toxicity of short antimicrobial peptides by adding positive charge amino acids and non-nature bulky amino acid β-naphthylalanine residues to their termini. Among the designed peptides, K4R2-Nal2-S1 displayed better salt resis...

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Detalles Bibliográficos
Autores principales: Chu, Hung-Lun, Yip, Bak-Sau, Chen, Kuan-Hao, Yu, Hui-Yuan, Chih, Ya-Han, Cheng, Hsi-Tsung, Chou, Yu-Ting, Cheng, Jya-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430538/
https://www.ncbi.nlm.nih.gov/pubmed/25970292
http://dx.doi.org/10.1371/journal.pone.0126390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430538/
https://www.ncbi.nlm.nih.gov/pubmed/25970292
http://dx.doi.org/10.1371/journal.pone.0126390

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