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Antibiotics in Early Life Alter the Gut Microbiome and Increase Disease Incidence in a Spontaneous Mouse Model of Autoimmune Insulin-Dependent Diabetes

Insulin-dependent or type 1 diabetes is a prototypic autoimmune disease whose incidence steadily increased over the past decades in industrialized countries. Recent evidence suggests the importance of the gut microbiota to explain this trend. Here, non-obese diabetic (NOD) mice that spontaneously de...

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Detalles Bibliográficos
Autores principales: Candon, Sophie, Perez-Arroyo, Alicia, Marquet, Cindy, Valette, Fabrice, Foray, Anne-Perrine, Pelletier, Benjamin, Milani, Cristian, Ventura, Marco, Bach, Jean-François, Chatenoud, Lucienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430542/
https://www.ncbi.nlm.nih.gov/pubmed/25970503
http://dx.doi.org/10.1371/journal.pone.0125448