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Antibiotics in Early Life Alter the Gut Microbiome and Increase Disease Incidence in a Spontaneous Mouse Model of Autoimmune Insulin-Dependent Diabetes
Insulin-dependent or type 1 diabetes is a prototypic autoimmune disease whose incidence steadily increased over the past decades in industrialized countries. Recent evidence suggests the importance of the gut microbiota to explain this trend. Here, non-obese diabetic (NOD) mice that spontaneously de...
Autores principales: | Candon, Sophie, Perez-Arroyo, Alicia, Marquet, Cindy, Valette, Fabrice, Foray, Anne-Perrine, Pelletier, Benjamin, Milani, Cristian, Ventura, Marco, Bach, Jean-François, Chatenoud, Lucienne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430542/ https://www.ncbi.nlm.nih.gov/pubmed/25970503 http://dx.doi.org/10.1371/journal.pone.0125448 |
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