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Notch Signaling Pathway Was Involved in Regulating Programmed Cell Death 1 Expression during Sepsis-Induced Immunosuppression

Programmed cell death 1 (PD-1) plays an important pathologic role in sepsis-induced immunosuppression. However, whether PD-1 overexpression occurs early during septic shock is unknown and its regulation mechanism is also unknown. Our study investigated the expressions of PD-1/programmed death-ligand...

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Detalles Bibliográficos
Autores principales: Pan, Tingting, Liu, Zhaojun, Yin, Jianyong, Zhou, Tianyun, Liu, Jialin, Qu, Hongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430661/
https://www.ncbi.nlm.nih.gov/pubmed/26063974
http://dx.doi.org/10.1155/2015/539841