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In Vitro and In Vivo Effects of Metformin on Osteopontin Expression in Mice Adipose-Derived Multipotent Stromal Cells and Adipose Tissue

Metformin is applied not only as antidiabetic drug, but also in the treatment of obesity or as antiaging drug. The first part of the research discussed the effect of metformin at concentrations of 1 mM, 5 mM, and 10 mM on the morphology, ultrastructure, and proliferation potential of mice adipose-de...

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Detalles Bibliográficos
Autores principales: Śmieszek, Agnieszka, Basińska, Katarzyna, Chrząstek, Klaudia, Marycz, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430663/
https://www.ncbi.nlm.nih.gov/pubmed/26064989
http://dx.doi.org/10.1155/2015/814896