Bromoenol Lactone, an Inhibitor of Calcium-Independent Phospholipase A(2), Suppresses Carrageenan-Induced Prostaglandin Production and Hyperalgesia in Rat Hind Paw

Prostaglandin (PG) E(2) and PGI(2) are essential to hyperalgesia in inflammatory tissues. These prostaglandins are produced from arachidonic acid, which is cleaved from membrane phospholipids by the action of phospholipase A(2) (PLA(2)). Which isozyme of PLA(2) is responsible for the cleavage of ara...

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Detalles Bibliográficos
Autores principales: Tsuchida, Keiichiro, Ibuki, Takae, Matsumura, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430671/
https://www.ncbi.nlm.nih.gov/pubmed/26063975
http://dx.doi.org/10.1155/2015/605727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430671/
https://www.ncbi.nlm.nih.gov/pubmed/26063975
http://dx.doi.org/10.1155/2015/605727

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