Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells

BACKGROUND: 17β-Oestradiol (E2)-induced reactive oxygen species (ROS) have been implicated in regulating the growth of breast cancer cells. However, the underlying mechanism of this is not clear. Here we show how ROS through a novel redox signalling pathway involving nuclear respiratory factor-1 (NR...

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Detalles Bibliográficos
Autores principales: Okoh, V O, Garba, N A, Penney, R B, Das, J, Deoraj, A, Singh, K P, Sarkar, S, Felty, Q, Yoo, C, Jackson, R M, Roy, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Full Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430710/
https://www.ncbi.nlm.nih.gov/pubmed/25965299
http://dx.doi.org/10.1038/bjc.2014.586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430710/
https://www.ncbi.nlm.nih.gov/pubmed/25965299
http://dx.doi.org/10.1038/bjc.2014.586

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