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Frequent MED12 mutations in phyllodes tumours of the breast

BACKGROUND: Phyllodes tumours are rare fibroepithelial tumours of the breast, that include benign, borderline, and malignant lesions. Although the molecular basis of phyllodes tumours largely remains unknown, a recent exome study identified MED12 mutations as a sole recurrent genetic alteration in f...

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Detalles Bibliográficos
Autores principales: Yoshida, M, Sekine, S, Ogawa, R, Yoshida, H, Maeshima, A, Kanai, Y, Kinoshita, T, Ochiai, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430713/
https://www.ncbi.nlm.nih.gov/pubmed/25839987
http://dx.doi.org/10.1038/bjc.2015.116