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Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts

BACKGROUND: Despite the recognised contribution of the stroma to breast cancer development and progression, the effective targeting of the tumor microenvironment remains a challenge to be addressed. We previously reported that normal fibroblasts (NFs) and, notably, breast cancer-associated fibroblas...

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Detalles Bibliográficos
Autores principales: Angelucci, C, Maulucci, G, Colabianchi, A, Iacopino, F, D'Alessio, A, Maiorana, A, Palmieri, V, Papi, M, De Spirito, M, Di Leone, A, Masetti, R, Sica, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430719/
https://www.ncbi.nlm.nih.gov/pubmed/25880005
http://dx.doi.org/10.1038/bjc.2015.135