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Transcriptional profiling of Foxo3a and Fancd2 regulated genes in mouse hematopoietic stem cells

Functional maintenance of hematopoietic stem cells (HSCs) is constantly challenged by stresses like DNA damage and oxidative stress. Foxo factors particularly Foxo3a function to regulate the self-renewal of HSCs and contribute to the maintenance of the HSC pool during aging by providing resistance t...

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Detalles Bibliográficos
Autores principales: Li, Xiaoli, Zhang, Tingting, Wilson, Andrew, Amarachintha, Surya, Sertorio, Mathieu, Pang, Qishen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430722/
https://www.ncbi.nlm.nih.gov/pubmed/25984447
http://dx.doi.org/10.1016/j.gdata.2015.04.011