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Transcriptional profiling of Foxo3a and Fancd2 regulated genes in mouse hematopoietic stem cells
Functional maintenance of hematopoietic stem cells (HSCs) is constantly challenged by stresses like DNA damage and oxidative stress. Foxo factors particularly Foxo3a function to regulate the self-renewal of HSCs and contribute to the maintenance of the HSC pool during aging by providing resistance t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430722/ https://www.ncbi.nlm.nih.gov/pubmed/25984447 http://dx.doi.org/10.1016/j.gdata.2015.04.011 |