Cargando…
Transcriptional profiling of Foxo3a and Fancd2 regulated genes in mouse hematopoietic stem cells
Functional maintenance of hematopoietic stem cells (HSCs) is constantly challenged by stresses like DNA damage and oxidative stress. Foxo factors particularly Foxo3a function to regulate the self-renewal of HSCs and contribute to the maintenance of the HSC pool during aging by providing resistance t...
Autores principales: | Li, Xiaoli, Zhang, Tingting, Wilson, Andrew, Amarachintha, Surya, Sertorio, Mathieu, Pang, Qishen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430722/ https://www.ncbi.nlm.nih.gov/pubmed/25984447 http://dx.doi.org/10.1016/j.gdata.2015.04.011 |
Ejemplares similares
-
In Vivo RNAi Screen Unveils PPARγ as a Regulator of Hematopoietic Stem Cell Homeostasis
por: Sertorio, Mathieu, et al.
Publicado: (2017) -
Hyper-active non-homologous end joining selects for synthetic lethality resistant and pathological Fanconi anemia hematopoietic stem and progenitor cells
por: Du, Wei, et al.
Publicado: (2016) -
The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5-mediated p53 arginine methylation
por: Du, Wei, et al.
Publicado: (2016) -
Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation
por: Chatla, Srinivas, et al.
Publicado: (2019) -
Fancb deficiency impairs hematopoietic stem cell function
por: Du, Wei, et al.
Publicado: (2015)