Ex vivo exposure of bone marrow from chronic kidney disease donor rats to pravastatin limits renal damage in recipient rats with chronic kidney disease

INTRODUCTION: Healthy bone marrow cell (BMC) infusion improves renal function and limits renal injury in a model of chronic kidney disease (CKD) in rats. However, BMCs derived from rats with CKD fail to retain beneficial effects, demonstrating limited therapeutic efficacy. Statins have been reported...

Descripción completa

Detalles Bibliográficos
Autores principales: van Koppen, Arianne, Papazova, Diana A, Oosterhuis, Nynke R, Gremmels, Hendrik, Giles, Rachel H, Fledderus, Joost O, Joles, Jaap A, Verhaar, Marianne C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430868/
https://www.ncbi.nlm.nih.gov/pubmed/25889756
http://dx.doi.org/10.1186/s13287-015-0064-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430868/
https://www.ncbi.nlm.nih.gov/pubmed/25889756
http://dx.doi.org/10.1186/s13287-015-0064-7

Ejemplares similares