Ex vivo exposure of bone marrow from chronic kidney disease donor rats to pravastatin limits renal damage in recipient rats with chronic kidney disease

INTRODUCTION: Healthy bone marrow cell (BMC) infusion improves renal function and limits renal injury in a model of chronic kidney disease (CKD) in rats. However, BMCs derived from rats with CKD fail to retain beneficial effects, demonstrating limited therapeutic efficacy. Statins have been reported...

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Detalles Bibliográficos
Autores principales: van Koppen, Arianne, Papazova, Diana A, Oosterhuis, Nynke R, Gremmels, Hendrik, Giles, Rachel H, Fledderus, Joost O, Joles, Jaap A, Verhaar, Marianne C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430868/
https://www.ncbi.nlm.nih.gov/pubmed/25889756
http://dx.doi.org/10.1186/s13287-015-0064-7

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