Cargando…

Frequency and distribution of Notch mutations in tumor cell lines

BACKGROUND: Deregulated Notch signaling is linked to a variety of tumors and it is therefore important to learn more about the frequency and distribution of Notch mutations in a tumor context. METHODS: In this report, we use data from the recently developed Cancer Cell Line Encyclopedia to assess th...

Descripción completa

Detalles Bibliográficos
Autores principales: Mutvei, Anders Peter, Fredlund, Erik, Lendahl, Urban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430925/
https://www.ncbi.nlm.nih.gov/pubmed/25907971
http://dx.doi.org/10.1186/s12885-015-1278-x