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Concordant and discordant DNA methylation signatures of aging in human blood and brain
BACKGROUND: DNA methylation is an epigenetic mark that balances plasticity with stability. While DNA methylation exhibits tissue specificity, it can also vary with age and potentially environmental exposures. In studies of DNA methylation, samples from specific tissues, especially brain, are frequen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430927/ https://www.ncbi.nlm.nih.gov/pubmed/25977707 http://dx.doi.org/10.1186/s13072-015-0011-y |