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Concordant and discordant DNA methylation signatures of aging in human blood and brain

BACKGROUND: DNA methylation is an epigenetic mark that balances plasticity with stability. While DNA methylation exhibits tissue specificity, it can also vary with age and potentially environmental exposures. In studies of DNA methylation, samples from specific tissues, especially brain, are frequen...

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Detalles Bibliográficos
Autores principales: Farré, Pau, Jones, Meaghan J, Meaney, Michael J, Emberly, Eldon, Turecki, Gustavo, Kobor, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430927/
https://www.ncbi.nlm.nih.gov/pubmed/25977707
http://dx.doi.org/10.1186/s13072-015-0011-y